Background & Aims: Dietary fat intake is related to the degree of obesity, but the specific
mechanisms by which fats regulate food intake in humans are unclear. We compared food
intake suppression, plasma triglyceride appearance, and cholecystokinin (CCK) response
after intestinal infusion of oils enriched with C18 fatty acids of increasing unsaturation.
Methods: Food intake and appetite changes after upper intestinal infusion of 0.9% saline,
20% Intralipid, and 20% emulsions of oils enriched with stearic, oleic, and linoleic acids …